Biographical Information:

Lingchong You joined the IGSP in 2004, and is an Assistant Professor in the Department of Biomedical Engineering at Duke. He was trained in Chemical Engineering (BE and PhD) and Molecular Biology (MS, Postdoctoral). His PhD research was carried out at the University of Wisconsin-Madison (supervisor: John Yin), focusing on mathematical modeling of biological systems and development of modeling tools and methods. He then did postdoctoral research at Caltech (supervisor: Frances H. Arnold), focusing on the design, modeling and experimental implementation & characterization of synthetic gene circuits.

Research Interests:

Synthetic gene circuits that can precisely program cellular behavior have great potential for applications in biotechnology, computation, environmental engineering and medicine. However, constructing synthetic gene circuits with reliable, non-trivial function is extremely difficult. A major challenge is to deal with cellular noise or the stochastic variability in gene expression, which is often due to small numbers of interacting molecules inside the cell. We are exploring general and scalable control strategies that will allow us to realize robust gene circuit function despite cellular noise and external perturbations. We approach this problem by using a combination of experimental and computational techniques.

Related Links
http://www.genome.duke.edu/people/faculty/you/