Gayathri Devi - Asst. Professor, Surgery & Pathology
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Gayathri Devi
Assistant Professor
Division of Experimental Surgery
Department of Surgery
Graduate Faculty and Secondary Appointment: Department of Pathology

Duke University Medical Center
Research Drive
Room 477 MSRB-I
Box 2606 DUMC
Durham, NC  27710

Phone (Office): 919 668 0410
Fax: 919 681 7970
Email: gayathri.devi@duke.edu

 
CURRICULUM VITAE
Education
1998-2000: Postdoctoral Fellowship (1998-2000): Oregon Health and Sciences, Portland, OR
1998: Ph.D. Biochemistry and Molecular Biology, University of Nebraska Medical Center, Omaha, NE
1993: Graduate studies Pharmacology, Southern Illinois University at Carbondale, IL
1993: M.S. Biochemistry, All India Institute of Medical Sciences, New Delhi, India
1991: B.S.Honors, Human Biology, All India Institute of Medical Sciences, New Delhi, India
 

Professional Experience

2005-: Assistant Professor, Duke University Medical Center
2002-2004: Principal Scientist, Cancer and Endocrine Program, AVI BioPharma, Inc., Corvallis, OR
2004-:  Affiliate Assistant Professor, Oregon State University, Corvallis, OR
2004-: Editorial Board Member, Current Pharmaceutical Biotechnology Journal
2004-: Member, Development Committee, Women in Endocrinology, Endocrine Society
2007-: Chair, Mentoring Committee, WE, Endocrine Society
 
Ad Hoc Reviewer for Scientific Journals: Cancer Gene Therapy, Molecular Cancer Therapeutics, Journal of Endocrinology, Clinical Cancer Research, Endocrinology, Current Opinion in Molecular Therapeutics, Current Opinion Invest. Drugs, Asian J of Andrology


Key Research Initiatives
  • elucidation of cross-talk mechanisms mediated by specific growth factor receptors (epidermal growth factor and insulin-like growth factor receptors) in regulating IAP expression and function in cancer models.
  • investigating protein-protein interactions between the IAPs and, in particular, their intrinsic negative regulator, XAF1.
  • understanding the mechanism of chemotherapy- and radiotherapy-resistance caused due to IAP expression and apoptotic failure in cancer cells
  • developing genomics and small-molecule inhibitor-based targeted strategies for modulation of apoptosis to overcome therapeutic resistance in cancer cells.

 

Related Links

Webpage:  http://surgery.duke.edu/modules/dept_surg_expsurg/index.php?id=5